The approach to architectural design is becoming more transdisciplinary, combining different sciences such as biology, chemistry and genetics. An emerging method of reconstruction from self-assembled biological materials was developed on the basis of the programmed genetic code with the help of which self-building and self-reconstruction will be possible. The abandoned business center "Zenit" in Moscow, Russia is our goal for the reconstruction. By 1995, it had been finished by 85%. This abandoned building has a height of 22 floors and a total area of 100 thousand square meters. The building is located near the city center and is easily visible from the surrounding areas.